In a step toward fighting solid tumors in children and young adults, Four Diamonds, Penn State College of Medicine and the Beat Childhood Cancer Research Consortium, along with Senhwa Biosciences, Inc. are launching a pioneering clinical trial. The study aims to evaluate the investigational drug, silmitasertib, in combination with FDA-approved drugs for solid tumors. “This clinical trial is a critical piece in understanding if the new medicine is safe to use in children as well as the mechanism of how the medicine works against the tumor cells,” said Dr. Chandrika Behura, study chair, Four Diamonds researcher and associate professor of pediatrics at the College of Medicine.